Search results for " gingival mesenchymal stem cells"

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Mesenchymal stem cells derived from inflamed dental pulpal and gingival tissue: a potential application for bone formation

2017

Background Chronic periodontal disease is an infectious disease consisting of prolonged inflammation of the supporting tooth tissue and resulting in bone loss. Guided bone regeneration procedures have become common and safe treatments in dentistry, and in this context dental stem cells would represent the ideal solution as autologous cells. In this study, we verified the ability of dental pulp mesenchymal stem cells (DPSCs) and gingival mesenchymal stem cells (GMSCs) harvested from periodontally affected teeth to produce new mineralized bone tissue in vitro, and compared this to cells from healthy teeth. Methods To characterize DPSCs and GMSCs, we assessed colony-forming assay, immunophenot…

Male0301 basic medicinePathologyCellular differentiationGingivaMedicine (miscellaneous)Bone tissue0302 clinical medicineOsteogenesisMedicinelcsh:QD415-436Pulpal and gingival mesenchymal stem cellsCells CulturedStem cell transplantation for articular cartilage repairlcsh:R5-920Heat shock proteinCell DifferentiationADFsMiddle AgedGingivitismedicine.anatomical_structureBone formationMolecular MedicineFemaleStem celllcsh:Medicine (General)Adultmedicine.medical_specialtyAdolescentBiochemistry Genetics and Molecular Biology (miscellaneous)Proinflammatory cytokinelcsh:Biochemistry03 medical and health sciencesstomatognathic systemHumansPeriodontitisBone regenerationDental PulpAgedProinflammatory cytokinesInflammationbusiness.industryResearchMesenchymal stem cellMesenchymal Stem Cells030206 dentistryCell BiologyDental diseaseInflammation Dental disease Pulpal and gingival mesenchymal stem cells Bone formation Heat shock protein ADFs Proinflammatory cytokinesstomatognathic diseases030104 developmental biologyCancer researchPulp (tooth)businessStem Cell Research & Therapy
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In Vitro and in Vivo investigation on stem cells isolated from pulp and gingival tissues from periodontally compromised teeth.

2016

dental pulp stem cells gingival mesenchymal stem cells bone regeneration periodontitisHuman medicine
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